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Lead Python Developer Jobs in Illinois, United States
430+ lead python developer jobs from 260+ companies hiring in Illinois, United States.
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Python Software Engineer
Chicago, Illinois, United States
$92k-$164k/yr HybridFull Time
8+ YOE2+ Mgmt8+ years software engineering; 5+ years cloud (AWS); 5+ years APIs/microservices; 3+ years Python production; 2+ years leading teams; 2+ years Terraform; 2+ years CI/CD; 1+ year containers.
Python, Terraform, AWS, Docker, Kubernetes, GitHub Actions, Jenkins, FastAPI, Flask, API Gateway, Lambda, DynamoDB
1mo
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Lead Software Engineer - Python
Westchester, Illinois, United States
RemoteFull Time
5+ YOEBachelor's degree or equivalent; 5+ years software engineering; proven delivery of programs on time and on budget; strong Python, C#/.NET, SQL; agile experience; effective communicator.
Python, C#/.NET, SQL, WCF, MVC, Entity Framework, Webservices
1w
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Technical Lead, Python Backend Engineer
United States
$85-$95/hr RemoteContract
6+ YOE2+ MgmtLead backend architecture and delivery of Python services on AWS; mentor team; ensure secure, scalable cloud-native systems.
Python, Javascript, SQL, REST API, OAuth 2, Docker, PostgreSQL, AWS, Kubernetes, EKS, Lambda, API Gateway, Jira, Bitbucket, GitHub, Slack, Teams, Pyramid, VSCode, Typescript, Snowflake, SQLAlchemy
1mo
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Lead Full Stack Engineer - React/Python
Chicago, Illinois, United States
$140k-$175k/yr HybridFull Time
7+ YOE7+ years in React, Python, and Node; REST & GraphQL; TypeScript; Jest; AWS/GCP; microservices; Git/Jira/Terraform; relational/noSQL databases; cloud logging and security.
React, Python, Node.js, REST, GraphQL, TypeScript, Jest, AWS, GCP, Terraform, Git, Jira, PostgreSQL, MySQL, Redshift, MongoDB, Redis, Cloud logging, Security tools
1mo
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Lead Software Engineer (Python, Java, JS, Postgres, MySQL, DynamoDB, Milvus/Pinecone)
McLean or Chicago
$179k-$225k/yr OnsiteFull Time
4+ YOELead software engineer with full stack skills (Python, JavaScript, Java), cloud (AWS), 4+ years software engineering, Bachelor's degree.
Python, Java, JavaScript, TypeScript, SQL, Go, HTML/CSS, Docker, Kubernetes, AWS
4d
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Lead GenAI Cloud Developer
United States
$94k-$149k/yr RemoteFull Time
5+ YOELead GenAI cloud developer for ElasticGPT; advanced agentic capabilities; Python/TypeScript; Elasticsearch; Kubernetes; cloud infra; GenAI systems.
Python, TypeScript, PyTorch, TensorFlow, Hugging Face, Elasticsearch, Kubernetes, Docker, LangGraph, LangSmith, n8n, OpenTelemetry, OpenAI, Anthropic, Vertex AI, BM25, vector search, Confluence, Jira, GitHub, ServiceNow
1w
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Lead Developer
United States
$111k-$211k/yr RemoteFull Time
7+ YOE7+ years software engineering experience; strong Java, Python, .NET; microservices, containers (Docker, Kubernetes); relational and NoSQL databases; REST/JSON; architectural design and CI/CD.
Java, Python, .NET, Docker, Kubernetes, REST, XML, JSON, CI/CD
1w
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Python Software Engineer
Chicago, Illinois, United States
$92k-$164k/yr HybridFull Time
8+ YOE2+ Mgmt8+ years software engineering; 5+ years cloud (AWS); 5+ years API/microservices; 3+ years Python; 2+ years leading teams; 2+ years Terraform; 2+ years CI/CD; 1+ years containers.
Python, Terraform, AWS, Docker, Kubernetes, GitHub Actions, Jenkins, FastAPI, Flask
2mo
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Lead Tools Engineer (Build & Infrastructure)
Timonium or United States
$128k-$156k/yr RemoteFull Time
Xsolla: Provides payment and monetization tools for video game developers.
5+ YOELeads design and development of internal tools for game development, build pipelines, and CI/CD; 5+ years in software engineering and tooling, strong C#/Python, Linux, and CI/CD experience.
C#, Python, Bash, Unity, AWS CDK, CloudFormation, Git, Linux
1mo
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Lead Software Engineer
United States
$165k-$175k/yr RemoteFull Time
10+ YOE10+ years of software development; API design; OpenAPI; AWS; Docker/Kubernetes; Python; real estate or financial services experience preferred.
Python, FastAPI, Vue.js, PostgreSQL, Redis, Docker, Kubernetes, AWS, Mapbox, OpenAPI
1w
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AI Engineer Lead
Chicago, Illinois, United States
$152k-$222k/yr HybridFull Time
5+ YOEMinimum 5 years Python development; 3+ years AI project experience focusing on productizing AI/ML solutions; strong ML fundamentals; GenAI with RAG, vector stores, agentic frameworks; data-driven; strong communication; hands-on AI/ML experimentation.
Python, APIs, Pipelines, AI orchestration, Java, React, LLM, GenAI, RAG, vector stores, SQL, SQL Server, Microsoft Fabric, Azure, Datadog, GitHub Copilot
2mo
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Lead Software Engineer (Full Stack)
Lincolnwood, Illinois, United States
$130k-$180k/yr RemoteFull Time
6+ YOELead full-stack engineer with 6+ years of experience, strong Python, API/integration, frontend JS, and cloud/container skills.
Python, Temporal, Celery, PostgreSQL, JavaScript, HTMX, Alpine.js, Docker, Kubernetes, Azure
3w
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Lead Software Engineer, Gen AI
Chicago or Peoria
$128k-$209k/yr OnsiteFull Time
Lead Software Engineer for Gen AI; Python, AWS, CI/CD, LangChain/LangGraph, FastAPI; collaboration with data scientists; production AI pipelines.
Python, GitHub Actions, AWS, SageMaker, Lambda, API Gateway, RDS, FastAPI, LangChain, LangGraph, Semantic Kernel, Crew.ai, Apache Airflow
5d
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Lead Java Software Engineer
Salt Lake City or United States
$85k-$160k/yr RemoteFull Time
8+ YOEBachelor’s or Master’s in CS/Engineering; 8+ years in software development; strong Java, Python, Spring Boot; cloud, microservices; AWS; CI/CD; Kubernetes.
Java, Python, Spring Boot, MySQL, NoSQL, OpenSearch, Elasticsearch, APM, Apache Camel, RabbitMQ, Data pipelines, AWS, CI/CD, Kubernetes, Microservices
4w
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Lead Software Engineer
United States
RemoteFull Time
7+ YOE7+ years building production web apps; backend in Python/Ruby on Rails; frontend in React; scalable, secure AI-enabled systems.
Python, Ruby on Rails, React, GCP, BigQuery, Kafka
2w
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Lead Software Engineer
United States
$155k-$195k/yr RemoteFull Time
6+ YOESenior software engineer with 6+ years’ Python experience; technical leadership; design, deployment, and scaling in microservices; strong cross-functional collaboration.
Python, Typescript, React, Databricks, Kafka, Domain Driven Design
2mo
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Lead Software Engineer
United States
$144k-$170k/yr RemoteFull Time
8+ YOE8+ years software engineering; BS/MS in CS; strong in C#/Java/Python; Azure; CI/CD; DevOps; production support experience.
CSharp, DOTNET, Java, Python, Azure, CI/CD, DevOps, Automated Testing
1w
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Lead AI Engineer
United States
RemoteFull Time
6+ YOESenior AI/ML engineer leading enterprise AI solutions; architecture, deployment, leadership.
Python, FastAPI, Azure, CosmosDB, Container Registry, Azure AI Search, Key Vault, Azure networking, React, Node.js, LangChain, LangGraph
2mo
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Senior Lead Software Engineer
United States
$130k/yr RemoteFull Time
6+ YOE2+ Mgmt6+ years of software development and 2+ years in leadership; strong OO design, Agile, CI/CD; Python/SQL stack; cloud/data tooling; GitHub practices.
Python, SQL, PostgreSQL, Aurora, Pandas, NumPy, Snowflake, Databricks, Docker, Airflow, GitHub
1mo
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Lead AI Engineer
United States
$95k-$170k/yr RemoteFull Time
5+ YOELead design and deployment of production-grade AI/ML systems for healthcare; ensure reliability, governance, and collaboration with stakeholders.
Python, PyTorch, TensorFlow, MLOps, NLP, LLMs, RAG, Azure, Epic EHR, Cogito, Nebula
3w
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Lead Data Engineer
Chicago, Illinois, United States
$98k-$182k/yr OnsiteFull Time
5+ YOE5+ years in big data pipelines; expertise in Spark; programming in Scala/Python; strong SQL; experience in cloud (AWS) with Databricks/EMR; able to own problems end-to-end; excellent communication.
Apache Spark, Scala, Python, SQL, AWS EMR, Databricks
2mo
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Lead LLM Engineer
United States
RemoteFull Time
6+ YOELead Azure-based LLM stack design, fine-tuning, and deployment; build retrieval pipelines; optimize performance and reliability.
Azure Machine Learning, AKS, FAISS, Pinecone, Python, Go, Java, Docker, Kubernetes, FastAPI, Flask, Azure AD, Key Vault, Azure Monitor, Grafana, LoRA, QLoRA, PEFT
1mo
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AI Enabled Lead Engineer
United States
RemoteFull Time
6+ YOE6+ years of full-stack/software engineering; backend APIs in Java/Python/Ruby; frontend in React/NextJS; relational and NoSQL DBs; REST, distributed systems; TDD and pair programming; Agile; client-facing; familiarity with AI tooling and LLM integration.
Java, Python, Ruby, React, NextJS, LangChain, LangGraph, CrewAI, AutoGen, LLM APIs, REST, SQL, NoSQL
1d
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Lead AI/ML Engineer, epocrates
United States
$148k-$252k/yr RemoteFull Time
5+ YOELead NLUP engineer with ML/AI expertise in healthcare; strong Python, DL frameworks, LLMs, and cloud experience; mentoring and cross-functional collaboration.
Python, PyTorch, TensorFlow, Transformers, GPT, RAG, SQL, PostgreSQL, AWS, Linux, Unix, Knowledge Graph, Kafka, Apache Spark, Docker, Kubernetes
1d
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Lead Software Engineer
United States
$220k-$240k/yr RemoteFull Time
6+ YOE6+ years of software engineering (backend or full-stack); strong Python and/or Java; experience with FastAPI and Spring Boot; API design, event-driven systems, and distributed architectures; AI-related experience; leadership; AWS, Kubernetes, and CI/CD familiarity; remote US work eligibility.
Python, Java, FastAPI, Spring Boot, REST, OAuth2, JWT, AWS, Kubernetes, CI/CD
2mo
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Lead Software Engineer, Security
United States
$170k-$248k/yr RemoteFull Time
5+ YOE5+ years in security engineering; proficient in Python, Go, C#; strong software engineering; leadership across security projects
Datadog, AWS, GitLab, Kubernetes, Hex, Looker, Redshift, CrowdStrike, C#, Go, Python, SQL, Terraform
10h
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Lead Software Engineer-AI Platform Engineer
Palo Alto or Jersey City or Hanover or Jersey City
$152k-$215k/yr HybridFull Time
5+ YOE5+ years software engineering; production code; cloud, AI/ML; Python/Go/Java/C#; automation; SDLC; IaC; collaboration.
Python, Go, Java, C#, Docker, Kubernetes, AWS, Azure, GCP, Terraform, MLflow, Prometheus, Grafana, PyTorch, TensorBoard, Linux, SQL, NoSQL
1mo
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Software Engineer/Lead Software Engineer
Bloomington or Tempe
HybridFull Time
Software Engineer with experience delivering software and leading collaborative initiatives in cloud-enabled environments.
Python, Terraform, APIs, JSON, React, AWS, Azure, Cloud Architecture, DevSecOps, Sagemaker, Lambda, EC2, SQS, S3, CloudFront, API Gateway, SNS
1mo
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Lead Data Engineer (Hypergiant)
United States
$137k-$180k/yr RemoteFull Time
10+ YOE10+ years software/data engineering; strong Python and TypeScript; databases and messaging; data fabric with Kafka; Docker/Kubernetes; Git/CI/CD; data modeling; US citizen with security clearance.
Python, TypeScript, Java, Bash, PostgreSQL, PostGIS, RabbitMQ, Apache NiFi, Apache Pulsar, Apache Kafka, Docker, Kubernetes, Git, Jenkins, Ansible, Terraform, JSON, GeoJSON, XML, YAML
3w
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AI Engineer Tech Lead - Sports Vertical
Morrisville or Chicago or Raleigh
$125k-$147k/yr HybridFull Time
8+ YOE8+ years AI/ML development, strong Python, deep learning frameworks, GPU optimization, real-time video analytics, NVIDIA stack.
Python, PyTorch, TensorFlow, NVIDIA CUDA, NVIDIA DeepStream, TensorRT, NVIDIA Blueprints, NVIDIA Omniverse, NVIDIA ACE
2mo
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Lead Field Engineer
United States
RemoteFull Time
Lead field integration, tooling development, and deployment of FPS with travel. Must be eligible to obtain U.S. government clearance.
JavaScript, Python, Go, Bash, FPS deployment tooling, deployment automation
2w
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Lead Data Engineer
Chicago, Illinois, United States
$180k-$200k/yr OnsiteFull Time
10+ YOELead architecture of scalable data platforms, mentor engineers, drive AI-enabled data products; strong AWS, Snowflake, Python/SQL, data governance.
Python, SQL, AWS, Snowflake, Cortex AI, Docker, Terraform, CloudFormation, Pulumi, CI/CD, Postgres, Aurora, LLM tools
2mo
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Lead Software Development Engineer
United States
$170k-$189k/yr RemoteFull Time
5+ YOEBachelor’s degree or 5–8 years in platform engineering, distributed systems, or software development; 3+ years designing scalable cloud-native services; AWS, microservices; AI coding tools; mentoring.
Java, Python, TypeScript, AWS, Docker, Kubernetes, PostgreSQL, MongoDB, Redis, Claude Code
1mo
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Lead Data Engineer
United States
$87k-$102k/yr RemoteFull Time
6+ YOE3+ MgmtLead architect and develop enterprise-scale data platforms; strong Databricks/Delta Lake in Azure; leadership and mentoring responsibilities.
Databricks, Delta Lake, Azure, Unity Catalog, Spark, SQL, Python, PySpark, Scala, R, CI/CD, Git, Terraform, Infrastructure as Code
1w
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Lead Software Engineer - Core AI
San Francisco or United States
$200k-$215k/yr RemoteFull Time
8+ YOE8+ years engineering experience with proficiency in C#, Java, JavaScript, Go, or Python; experience with generative AI, LLMs, and cloud infrastructure; strong architecture and mentoring.
C#, Java, JavaScript, Go, Python, Generative AI, LLMs, MCP, LangGraph, OpenAI, Bedrock, Cloud infrastructure
2w
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Lead GCP Engineer: AI Platforms & Development
United States
$122k-$192k/yr RemoteFull Time
8+ YOE8+ years backend software engineering; 3+ years on Google Cloud Platform; expert in Python and/or Go; experience with Gemini, Vertex AI SDKs, ADK, and CI/CD.
Python, Go, Vertex AI, Gemini, ADK, Terraform, BigQuery, Vertex AI SDK, Cloud Run, GKE, Cloud Functions
1mo
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Lead Machine Learning Engineer
United States
RemoteFull Time
8+ YOE8+ years software/ML experience; 3+ years leadership; production ML deployment; PyTorch/TensorFlow; Python; cloud; containers; MLOps; strong English; CS/ML degree.
PyTorch, TensorFlow, Python, Docker, Kubernetes, AWS, Azure, GCP, MLops, Feature Stores, Model Monitoring
3w
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Lead Data Engineer
Chicago, Illinois, United States
$98k-$182k/yr HybridFull Time
5+ YOE5+ years in developing big data pipelines; strong Spark, Scala and Python; SQL proficiency; cloud experience (AWS); able to own issues and translate business requirements into technical solutions.
Apache Spark, Scala, Python, AWS EMR, Databricks, SQL
3w
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Lead Information Security Software Engineer (ISE)
United States or Ohio
$82k-$173k/yr RemoteFull Time
4+ YOELead role developing API-driven security tools; expert in multiple languages; cloud and security tooling experience.
Python, JavaScript, Java, C/C++, C#, Go, API, Vue.js, Angular, React, FastAPI, Django, AWS, Splunk, Elasticsearch, EDR, SIEM, SOAR, XDR
2mo
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Test Automation Engineer Lead
United States
$129k-$215k/yr RemoteFull Time
8+ YOE3+ MgmtLead a small automation team; design and implement scalable test automation frameworks; hands-on leadership with CI/CD focus.
Python, Selenium, Cypress, Playwright, Postman, CI/CD, AWS, Azure, GCP, GitHub Actions, Azure DevOps
HiringCafe market data
Lead Python Developer Jobs market signals in Illinois, United States
These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.
Open jobs
430+
Hiring companies
260+
Fresh sample
53% new in 30d
Salary visibility
81% show pay
Companies appearing in this market
UnitedHealth GroupAllstateCapital OneCaterpillarResource InnovationsCodalJPMorgan ChaseLenovo
Work location mix in visible results
Remote: 47Hybrid: 13Onsite: 12
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