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Lead Python Developer Jobs in Illinois, United States

430+ lead python developer jobs from 260+ companies hiring in Illinois, United States.

432 jobs- Illinois
2w
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Security Lead Software Engineer
Elmhurst, Illinois, United States
$235k-$310k/yr OnsiteFull Time
McMaster-Carr
McMaster-Carr: Supplies maintenance, repair, and operations products to industrial customers.
Hands-on security operations, vulnerability management, and scripting in Python/PowerShell; experience across detection, response, and cloud security.
Splunk, Tenable, Carbon Black, Symantec, Active Directory/Entra ID, ForeScout, Proofpoint, Checkpoint, Wireshark, tcpdump, Python, PowerShell, Azure, Linux, Kubernetes, Cisco ACI, GitLab, VMware, Copilot, OpenAI, Gemini, Claude
2mo
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Lead Site Reliability Engineer
United States
$148k-$185k/yr RemoteFull Time
DraftKings
DraftKingsNASDAQ: DKNG: Operates digital sports betting, fantasy sports, and casino gaming platforms.
6+ YOESix plus years in distributed cloud environments, Kubernetes, IaC, Go/Python automation, Linux performance, and multi-cloud deployment.
Kubernetes, Docker, Go, Python, Terraform, Ansible, Chef, Linux, AWS, GCP, vSphere, Nutanix
5d
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Lead Assistant Manager - GenAI Developer
United States
RemoteFull Time
EXL
EXLNASDAQ: EXLS: Provides data analytics and digital operations solutions to businesses.
2+ YOEBachelor’s/Master’s degree in Computer Science, AI, Data Science; 2-4 years in AI/ML with 3+ years in Generative AI; strong LLMs/GANs/diffusion/RAG; proficient in Python, PyTorch/TF/Hugging Face; cloud platforms (AWS/Azure/GCP).
Python, PyTorch, TensorFlow, Hugging Face, AWS, Azure, GCP, LLMs, GANs, Diffusion models, RAG
3w
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Lead Cloud Platform Engineer
United States
$103k-$191k/yr RemoteFull Time
Centene
CenteneNYSE: CNC: Provides government-sponsored and commercial healthcare insurance programs and services.
5+ YOE5–7 years in cloud platforms; Azure and AWS experience; IaC/automation; DevOps/CI-CD tooling; Docker/Kubernetes; scripting (PowerShell, Python)
Azure, Amazon Web Services, Gitlab, Terraform, CloudFormation, Cloud Deployment Manager, Docker, Kubernetes, Cloud Foundry, Swarm, PowerShell, Python, Packer, Azure Resource Manager (ARM) templates
1mo
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US E ES - Lead Full Stack Engineer - PxE (PARENT Req)
United States
$106k-$210k/yr RemoteFull Time
Deloitte
Deloitte: Provides professional audit, consulting, advisory, and tax services.
5+ YOELead Full-stack engineer with 5+ years in multiple languages, cloud-native engineering, and DevSecOps; bachelor’s degree required.
Angular, React, NodeJS, Python, Streamlit, C#, .NET Core, Golang, SQL, NoSQL
5d
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Lead AI Automation Engineer
North Chicago, Illinois, United States
$110k-$209k/yr HybridFull Time
AbbVie
AbbVieNYSE: ABBV: Develops and sells innovative pharmaceutical and biopharmaceutical medicines.
7+ YOEBachelor’s with 7+ years or Master’s with 6+ years or PhD with 2+ years; Python expert; AI/ML framework experience; production-grade software delivery; strong communication; mentoring capability.
Python, AI/ML frameworks, Enterprise integration tools, Cloud platforms
2w
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Service Enablement Engineer Lead
United States
RemoteFull Time
NWN Carousel
NWN Carousel: Provides AI-powered cloud communications and hybrid workplace technology solutions.
Designs onboarding, automation, and enablement processes; collaborates cross-functionally; leads and mentors teams; strong IT and cloud expertise.
AWS, Azure, GCP, OpsRamp, Zenoss, Nectar, ITIL, Microsoft Office, Python, PowerShell, Ansible, CCNP, MCSE
1d
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Lead Engineer – Thermal Mechanical
Wilmington or United States
$98k-$164k/yr RemoteFull Time
GE Vernova
GE VernovaNYSE: GEV: Designs and services technologies for global power generation and electrification.
4+ YOEBachelor’s in engineering; 4+ years in technology/engineering; 2+ years in thermal-mechanical or nuclear fuel analysis; Python and FORTRAN; NRC submittal experience preferred; strong communication; travel <10%; relocation optional.
Python, FORTRAN
1w
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Lead Structural Engineer 2 - Nuclear
United States
$132k-$205k/yr RemoteFull Time
Sargent & Lundy
Sargent & Lundy: Provides engineering and consulting services for the power industry.
12+ YOELead structural engineer with ABET BSCE, 12+ years, proficiency in STAAD/SAP2000/ANSYS, ASCE 7/AISC/ACI, PE or SE license.
STAAD, SAP2000, SAFE, STRUDL, ANSYS, ASCE 7, AISC, ACI, Python, MATLAB, Excel
2w
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Staff Software Engineer - Developer Experience
United States
RemoteFull Time
Seeq
Seeq: Analyzes industrial process data to improve manufacturing performance.
8+ YOE8+ years in developer experience, platform tooling, or SDK; strong Java, Python, TypeScript, or Go; cloud/CI-CD; lead initiatives; collaborate across teams.
Java, Python, TypeScript, Go, AWS, Azure, GCP, CI/CD
3w
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Lead Sr Staff Software Engineer - Front End Fundamentals
Bellevue or Boulder or Chicago or Denver or Irvine or Los Angeles or New York or San Francisco or San Jose or Seattle or Ventura
$166k-$305k/yr HybridFull Time
The Trade Desk
The Trade DeskNASDAQ: TTD: Cloud-based programmatic advertising platform for data-driven media buying.
13+ YOE1+ MgmtSenior frontend leadership role requiring 13+ years of software development, 1+ year of people management, strong TypeScript/JavaScript or other languages, cloud and distributed systems experience, and mentoring.
TypeScript, JavaScript, C#, Java, C, C++, Python, SQL, Scala
1mo
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Lead Data Engineer – Financial Data, Compliance & Business Intelligence
Chicago or Washington or Sarasota or Hartford or Costa Mesa or San Jose or Atlanta or Boston or Cleveland or Columbus or Dallas or Fort Lauderdale or Fort Wayne or Grand Rapids or Indianapolis or Los Angeles or Miami or New York City or Oak Brook Terrace or Sacramento or San Francisco or South Bend or Tampa or Houston or Austin
$111k-$226k/yr OnsiteFull Time
Crowe
Crowe: Global professional services firm providing audit, tax, and consulting.
3+ YOE3+ years ETL development; experience with Bank Secrecy Act/AML regulations; consulting experience; strong ETL/EDW skills; Python/Java; cloud data warehousing (Azure/AWS/Snowflake); excellent communication and teamwork.
ETL tools, Python, Java, Azure, AWS, Snowflake
1w
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Gravitee Developer/Lead - Senior Software Engineer (Chicago, IL, US)
Chicago, Illinois, United States
$73k-$174k/yr HybridFull Time
Capgemini
CapgeminiEuronext Paris: CAP: Provides global IT consulting and digital transformation services.
10+ YOE10+ years in API/cloud/integration engineering; strong AWS API Gateway and Gravitee; Kubernetes; Terraform; Java/JavaScript/Python/.NET; Cloud Run/Functions; Docker.
AWS API Gateway, Gravitee API Management, GCP Cloud Run, GCP Cloud Functions, Kubernetes, Docker, Terraform, Java, JavaScript, Python, NET, Cloud Run, Cloud Functions
4w
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Tech Lead
United States
RemoteFull Time
Iris.ai
Iris.ai: AI platform for scientific research and enterprise knowledge management.
7+ YOE2+ Mgmt7+ years software development; 2+ years leadership; 3+ years Python; Django/Flask; REST APIs; cloud; English fluency.
Python, Django, PostgreSQL, Elasticsearch, OpenSearch, ChromaDB, Couchbase, Gensim, Torch, Transformers, spaCy, Autogen, AWS, Windsurf, Cursor, Amazon Q, Claude, Git, CI/CD
2mo
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Lead Network Engineer
United States
$112k-$156k/yr RemoteFull Time
HealthEdge
HealthEdge: Cloud-based administrative software for healthcare insurance providers.
7+ YOE1+ Mgmt7+ years of hands-on network engineering in enterprise environments; 1-2 years of people leadership; strong enterprise networking, security, and vendor management.
Cisco, Aruba, Palo Alto, Meraki, SD-WAN, VPN, VLAN, AWS, Azure, Python, Ansible
2mo
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Lead Cybersecurity Engineer
Chicago, Illinois, United States
$115k-$175k/yr OnsiteFull Time
Corient
Corient: Provides wealth management services for high-net-worth individuals and families.
10+ YOETen+ years in cybersecurity engineering/architecture with strong Azure, identity and network security experience; proficient in IAM, EDR, SIEM, CASB, ZTNA, and secure IaC practices.
Azure, Active Directory, SQL, Office365, Windows Server, PowerShell, Python, Terraform, CloudFormation, EDR, IAM, SOAR, SIEM, DLP, ZTNA, NGFW
2mo
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Lead Security Engineer
United States
$135k-$288k/yr RemoteFull Time
GoodRx
GoodRxNasdaqGS: GDRX: Platform for comparing and saving on prescription drug prices.
8+ YOE8+ years in cybersecurity or security engineering; deep expertise in application and cloud security; experience with DevSecOps, secure design, risk assessments, and incident response.
AWS, GCP, JavaScript, CI/CD, SAML, Okta, SIEM, Kubernetes, Python, Go, Rust
1w
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Lead Value Engineer
United States
RemoteFull Time
SingleStore
SingleStore: Real-time distributed SQL database for transactions and analytics.
7+ YOE7+ years technical pre-sales/value engineering; Masters or MBA with relevant experience; strong comms for C-Suite; SQL, analytics tools; cloud platforms; large-scale DBs.
ANSI SQL, Excel, Python, AWS, Azure, GCP, VMware
1d
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Lead DevOps Engineer
United States
$90k-$145k/yr RemoteFull Time
Hilton
HiltonNYSE: HLT: Operates and franchises a global portfolio of hotels and resorts.
5+ YOEFive years in technology; four years with CI tools; three years Kubernetes; three years on AWS; scripting in Bash; on-call reliability experience; travel up to 10%.
GitLab, Bamboo, CI/CD tooling, Kubernetes, Docker, Terraform, Python, Shell, JavaScript/Java
1mo
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Fullstack Engineer
United States
$150k-$225k/yr RemoteFull Time
OLarry
OLarry: AI-powered tax planning and compliance for high-net-worth individuals.
Lead fullstack development with React/Next.js, Node.js/Python, REST APIs; cloud (AWS/GCP); fintech experience preferred; agile Design Sprint; leadership.
React, Next.js, Node.js, Python, REST APIs, AWS, Google Cloud, Figma, SQL, NoSQL
2w
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Lead Developer - Data, AI, & Wealth Tech Platforms - Chicago, IL
Chicago or Lincolnshire or Rockford
$125k-$175k/yr HybridFull Time
Savant Wealth Management
Savant Wealth Management: Independent fiduciary firm providing comprehensive wealth management and planning.
7+ YOE7+ years data engineering; Bachelor's in CS/IS/Data Eng or equivalent; strong Microsoft Azure; production data pipelines; SQL & Python; experience with AI/ML data workflows and enterprise feeds.
Microsoft Azure, Azure Fabric, SQL, Python, PySpark, Spark
1mo
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Fullstack Engineer
United States
$150k-$225k/yr RemoteFull Time
OLarry
OLarry: AI-powered tax advisory platform for high-net-worth individuals and businesses.
Lead fullstack development with React/Next.js; backend Node.js/Python; REST APIs; SQL/NoSQL; cloud (AWS/GCP); fintech familiarity; agile Design Sprint.
React, Next.js, Node.js, Python, REST APIs, SQL, NoSQL, AWS, Google Cloud, Figma
1mo
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Principal Developer - IT
Chicago, Illinois, United States
$141k-$183k/yr OnsiteFull Time
United Airlines
United AirlinesNASDAQ: UAL: Operates a global network of passenger and cargo flights.
7+ YOELead hands-on principal developer with 7-10+ years in IT solutions architecture; strong experience in CDP, identity graphs, AWS, Java/Python/.NET; design scalable, data-driven platforms with privacy compliance.
AWS, Java, Python, .NET, CDP, Identity Graph, Neptune Graph DB, Gremlin, Cypher
1d
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Lead Data Engineer - Generative AI
Charlotte or Columbus or Chicago or Hartford
$135k-$203k/yr HybridFull Time
The Hartford
The HartfordNYSE: HIG: Provides business and personal insurance, group benefits, and investments.
8+ YOE8+ years Python; 7+ years data engineering with SQL/NoSQL, Snowflake, ETL/ELT, CI/CD, Big Data; 3+ years GenAI; 2+ years production GenAI data solutions; 3+ years RAG pipelines; 3+ years vector and graph DBs; 3+ years unstructured data for GenAI; 3+ years AI data pipelines with structured/semi/unstructured data.
Python, SQL, NoSQL, Snowflake, ETL/ELT, CI/CD, Big Data, AWS, Google Cloud, Azure, Spark, Vertex AI, S3, Langchain, Langgraph
4w
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Lead Engineer- Advanced Computational Methods for Power Systems (62577)
United States
$105k-$154k/yr RemoteFull Time
Eaton
EatonNYSE: ETN: Manages electrical, hydraulic, and mechanical power systems globally.
PhD or PhD candidate within 6 months; or Master's with 3 years experience; or Bachelor's with 5 years; strong Python/MATLAB and ML experience; no immigration sponsorship accepted.
Python, MATLAB, PyTorch, TensorFlow, Google Cloud, Docker, Kubernetes
3w
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Senior Technical Lead/Software Engineer IV (CHICAGO, IL, US, 60654-4203)
Chicago, Illinois, United States
$146k-$244k/yr HybridFull Time
Grainger
GraingerNYSE: GWW: Distributes maintenance, repair, and operating supplies to businesses.
Experience leading software engineering in hybrid cloud, containerization, DevOps, architecture input, and team leadership.
Kubernetes, AWS, GCP, Azure, Terraform, CloudFormation, Jenkins, Git, Python, Go, Java, Ansible, Terraform, Docker, APIs, CI/CD
1mo
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Sr. Lead Software Engineer - 11282
United States
$149k-$194k/yr RemoteFull Time
Coupa
Coupa: Cloud-based platform for managing and optimizing business expenditures.
10+ YOE8-10+ years in software/platform engineering; strong Python/SQL; data ingestion and pipelines; cloud (AWS/GCP/Azure); Databricks/BigQuery/Snowflake; Lakehouse; experience with Presto/Trino; Iceberg/Delta Lake.
Python, SQL, Databricks, BigQuery, Snowflake, Presto, Trino, Iceberg, Delta Lake, AWS, GCP, Azure
1mo
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Software Architect- Python
Chicago, Illinois, United States
$170k-$193k/yr HybridFull Time
Hub International
Hub International: Provides global insurance brokerage and risk management services.
8+ YOE8+ years Python software development; 2+ years in architect/tech lead; cloud-native Azure/AWS; design of scalable backend, microservices, APIs; stakeholder engagement; AI workflows.
FastAPI, Django, Flask, SQLAlchemy, Pydantic, Celery, pytest, React, Angular, Azure, AWS, Terraform, Bicep, CDK, Kafka, Azure Service Bus, SQS, Git, CI/CD, LangChain, LangGraph, OpenAI, LangChain
5d
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AI Red Team Lead Engineer
Minneapolis or Atlanta or Cincinnati or New York or Chicago or Gresham or Charlotte or Irving or Earth City
$133k-$157k/yr HybridFull Time
U.S. Bank
U.S. BankNYSE: USB: Provider of personal, business, and institutional financial services.
8+ YOELead AI red team operations; design, execute, and report on AI/ML security testing; mentor engineers; strong cybersecurity and AI knowledge.
Python, PowerShell, Go, C++, Shell
3w
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Lead Cloud Engineer (P486)
Cincinnati or Chicago
$125k-$207k/yr HybridFull Time
84.51°
84.51°NYSE: KR: Provides retail data analytics and targeted advertising services.
5+ YOE5+ years on Azure, IaC (Terraform/OpenTofu), SDLC with Agile; 4-year technology degree; Azure Administrator certification preferred; Docker/Kubernetes experience a plus.
Terraform, Spacelift, OpenTofu, Kubernetes, AKS, Docker, Helm, GitHub Actions, Datadog, Artifactory, Python
8h
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Lead Infrastructure Engineer III
Boise or United States
$130k-$140k/yr RemoteFull Time
Truckstop
Truckstop: Provides a digital marketplace for freight matching and logistics.
8+ YOEExtensive cloud infrastructure experience with Kubernetes, Terraform, IaC, automation, monitoring, security, and leadership.
Kubernetes, AKS, EKS, Terraform, Chef, Packer, Puppet, New Relic, Azure, AWS, GitLab, GitHub Actions, PowerShell, Python, YAML, Kafka, .NET, Node.js, Linux, IAM, REST, GraphQL
2w
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Lead Software and Data Engineer
Chicago, Illinois, United States
$155k-$200k/yr HybridFull Time
William Blair
William Blair: Provides investment banking, investment management, and private wealth services.
5+ YOE5+ years software/data engineering; strong Python; Dagster; Azure Synapse; Kubernetes; data lake; PySpark; SQL; Azure cloud; Databricks; AI tool familiarity.
Dagster, Azure Synapse, PySpark, Kubernetes, Python, Dagster Cloud, Databricks, Spark, GitHub Copilot, Claude Code
1w
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Staff Software Engineer - Back End (Remote)
United States
$125k-$145k/yr RemoteFull Time
Ad Hoc
Ad Hoc: Providing user-centered digital services to federal government agencies.
9+ YOE9+ years of engineering; Python, Django; API integration; backend development; independently lead delivery.
Python, Django, APIs
1mo
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Sr. Software Engineer
United States
$100k-$160k/yr RemoteFull Time
Learning.com
Learning.com: Provides K-12 digital literacy and computer science curriculum.
5+ YOE5+ years of software development; senior/lead experience; strong full-stack skills; React/Angular; C#, Python, JavaScript; SQL and microservices; remote-ready; excellent communication.
C#, Python, JavaScript, React, Angular, SQL, REST APIs, Microservices
1mo
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Tech Lead - Senior Software Engineer
New York or United States
$200k-$230k/yr RemoteFull Time
YipitData
YipitData: Providing alternative data and research for institutional investors.
6+ YOE2+ Mgmt6+ years software development; 2+ years in technical leadership; shipped SaaS; strong system design; stack: Python, TypeScript/React, AWS; AI-native workflows; Bachelor's or Master's in CS or STEM.
Python, TypeScript, React, AWS, Databricks, Claude Code, Cursor, Codex
2mo
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Senior Software Engineer
United States
$94k-$179k/yr RemoteFull Time
Mercury Insurance
Mercury InsuranceNYSE: MCY: Provides personal and commercial property and casualty insurance products.
5+ YOEBachelor’s degree in CS/IS or related field; 5+ years software development; 2+ years leading/mentoring teams; strong Java/Python/Go/JavaScript; AWS, Kafka are a plus; CI/CD experience; cloud familiarity.
Java, Python, Go, C++, JavaScript, Apache Kafka, AWS, S3, Docker, Kubernetes, NI Fi, SQS, REST, gRPC, CI/CD
1mo
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Lead AI & Data Infrastructure Engineer
United States
$140k-$175k/yr RemoteFull Time
Matium
Matium: Digital marketplace for industrial raw material trading.
6+ YOE6+ years in data engineering, ML or applied AI; proficient in Python, SQL, data stack; experience deploying ML models; familiarity with recommender systems/marketplace algorithms; distributed data systems; scalable data pipelines; startup environment.
Python, SQL, Cloud platforms, Data pipelines, Machine learning, Big data technologies
4w
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Software Engineer, Growth
North America
$90k-$230k/yr RemoteFull Time
Monarch Money
Monarch Money: A subscription-based platform for personal budgeting and wealth management.
5+ YOE5+ years software engineering; Python, TypeScript, React; lead complex projects; remote collaboration.
Python, TypeScript, React, A/B testing, Analytics
1w
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Digital Technology Lead – Vin & Catalog Modernization
Lisle, Illinois, United States
$138k-$206k/yr OnsiteFull Time
International Motors
International Motors: Manufacturer of commercial trucks, buses, and transportation solutions.
7+ YOE1+ MgmtBachelor's or Master's in a related field with strong software engineering experience; 7+ years total, 3+ years leading; experience with modern backend languages, data-intensive apps, and microservices.
Node.js, TypeScript, Python, Java, Cloud-native databases, Elasticsearch, Algolia
1w
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Sr. Staff AI/ML Engineer
Portland or San Francisco or Chicago or Boston or Seattle or Dallas
$220k-$256k/yr RemoteFull Time
WEX
WEXNYSE: WEX: Provides global payment processing and business information management services.
12+ YOELead development of production AI systems; 12+ years in software/ML; Python, PyTorch/TF; cloud platforms; IaC; CI/CD; Bachelor's (Master preferred).
Python, PyTorch, TensorFlow, NumPy, Pandas, scikit-learn, LangChain, ADK, AWS, Azure, GCP, Terraform, GitHub Actions

HiringCafe market data

Lead Python Developer Jobs market signals in Illinois, United States

These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.

Open jobs
430+
Hiring companies
260+
Fresh sample
58% new in 30d
Salary visibility
91% show pay

Companies appearing in this market

AbbVieSargent & LundyThe HartfordMercury Insurance84.51°DeloitteDraftKingsOLarry

Work location mix in visible results

Remote: 33Hybrid: 16Onsite: 6