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Lead Python Developer Jobs in Illinois, United States

430+ lead python developer jobs from 260+ companies hiring in Illinois, United States.

432 jobs- Illinois
1mo
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Staff Analytics Engineer - US (Remote)
United States
$180k-$220k/yr RemoteFull Time
Luxury Presence
Luxury Presence: AI growth platform for real estate agents and brokerages.
8+ YOE8+ years in analytics/data engineering; strong SQL, dbt, Snowflake; data architecture; lead analytics initiatives; collaborate with stakeholders.
dbt, SQL, Python, Snowflake, Airflow, Sigma, Hex
1mo
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Principal Product Analytics Engineer
United States
$195k-$312k/yr RemoteFull Time
Toast
ToastNYSE: TOST: Cloud-based technology platform for the restaurant and hospitality industry.
12+ YOELead architecture of product analytics data ecosystem; build scalable data infrastructure; collaborate across product and engineering teams.
Amazon S3, Airflow, dbt, Snowflake, Hex, Sigma, Amplitude, Python, SQL, Claude, Cursor, ChatGPT, MCP
2w
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Senior Information Engineer Manager
Schaumburg, Illinois, United States
OnsiteFull Time
Fulcrum Global Technologies
Fulcrum Global Technologies: Provides business management software for legal and professional firms.
7+ YOE3+ MgmtLead design and management of security controls; oversee IAM, MFA, SSO; implement malware protection, DLP, and vulnerability management.
IAM, MFA, SSO, PAM, EDR, XDR, DLP, PACS, Terraform, Python, PowerShell, Bash, SAML, OAuth 2.0, OIDC, PKI
2mo
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Associate Forward Deployed Engineer (L3)
United States
RemoteFull Time
Symmetry Systems
Symmetry Systems: Protects enterprise data and AI through automated visibility and control.
1+ YOE1-5+ years in forward deployed, solutions architect, or related roles; able to lead enterprise technical engagements; proficient with AWS/Azure/GCP; strong debugging and API/integration skills.
AWS, Azure, GCP, Python, Go, TypeScript, IAM, APIs
2mo
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Senior Managed Services Engineer
United States
$65k-$105k/yr RemoteFull Time
CommandLink
CommandLink: Provides integrated cloud networking, security, and communication solutions.
7+ YOE7-10 years of enterprise network engineering in managed services; strong SD-WAN and SASE expertise; experience with Cato, Fortinet, Versa, Cisco Meraki; UCaaS (MetaSwitch); ability to mentor engineers and lead network transformations.
SD-WAN, SASE, Cato Networks, Fortinet FortiGate, FortiManager, FortiSASE, Versa Networks, Cisco Meraki, MetaSwitch, UCaaS, ZTNA, WAN optimization, Python, Ansible, RESTful APIs
1d
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Senior/Lead Data Scientist (Supply Chain)
Plano or United States
RemoteFull Time
Tiger Analytics
Tiger Analytics: Provides AI and advanced analytics consulting for global enterprises.
8+ YOE8+ years in Data Science or analytics; strong Python with NumPy/Pandas/SciPy/scikit-learn; PySpark; supply chain domain experience; model development lifecycle; strong communication.
Python, PySpark, NumPy, Pandas, SciPy, scikit-learn
2mo
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Software Engineering Manager
United States
$139k-$174k/yr RemoteFull Time
Ancestry
Ancestry: Provides online genealogy research and consumer DNA testing services.
10+ YOE3+ Mgmt10+ years in software development, 3+ years in management; Agile/Scrum; Java, Python, SQL; SOA and scalable architectures; AI impact on SDLC; Bachelor’s in CS or CE; willing to lead onshore and offshore teams.
Java, Python, SQL, Spring Boot
1mo
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Embedded Software Development Manager
Toronto or United States
RemoteFull Time
Kepler Communications
Kepler Communications: Provides real-time internet connectivity via a network of satellites.
5+ YOE3+ Mgmt5+ years embedded software, 3+ years leading software teams, strong C/C++/Python, embedded Linux/bare-metal, cross-functional leadership.
C, C++, Python, Embedded Linux, Bare-metal
2mo
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Engineering Manager, Data Science (Remote, Continental United States)
Arlington or United States
RemoteFull Time
International Consulting Associates
International Consulting Associates: Data science and research services for federal health agencies
5+ YOE5+ MgmtLead data science teams; hands-on DS; Python/SQL; cloud; Agile; bachelor in quantitative field; ability to obtain Public Trust.
Python, SQL, Azure, AWS, GCP, Machine Learning Frameworks
2mo
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Senior Manager - Software Engineering - TeraWave
United States or California or Washington
$197k-$276k/yr RemoteFull Time
Blue Origin
Blue Origin: Manufactures reusable rockets and infrastructure for human space exploration.
5+ YOE5+ Mgmt5+ years leading software engineering teams; proven scalable production systems; strong CS fundamentals; experience with GitLab, Kubernetes, CI/CD, Next.js, Python; cloud (AWS, Azure, GCP).
GitLab, Kubernetes, CI/CD, Next.js, Python, AWS, Azure, Google Cloud Platform
1mo
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Engineering Manager, Product Experience (PX)
United States
$145k-$217k/yr RemoteFull Time
Istari Digital: Provides digital engineering software for aerospace and defense industries.
8+ YOE3+ Mgmt8+ years software engineering; 3+ years leading teams; customer-facing product work; strong JS/TS (React, Node.js); Python or Go backend; AI-enabled features; secure or regulated environments.
JavaScript, TypeScript, React, Node.js, Python, Go, LLMs
4w
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Director of Scientific Affairs
United States
RemoteFull Time
XRHealth
XRHealth: Delivers therapeutic healthcare through immersive virtual reality and telehealth.
5+ YOE3+ MgmtPh.D. or equivalent; proven grant writing; experience leading RCTs; publications; Python/R; SQL; bridge academia and health-tech.
Python, R, SQL, Cloud-Based Data Warehouse, AI Platforms
1w
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Manager, Analytics & Reporting
United States
$107k-$145k/yr RemoteFull Time
Personify Health
Personify Health: Personalized platform for health plan administration and employee wellbeing.
5+ YOE2+ MgmtLead analysts team; develop client reporting; analyze health data; strong SQL & Python; present to diverse audiences.
SQL, Python
2mo
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Engineering Manager
North America
RemoteFull Time
Plata: Digital banking platform providing credit cards and financial services.
3+ YOE3+ Mgmt3+ years leading engineering teams; AI/ML or data-driven engineering experience; hands-on development background; ability to translate product requirements into technical solutions; strong cross-team communication; English proficiency of at least B1.
AI, Backend, Cloud, Python, SQL
1w
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Senior Machine Learning Research Scientist
United States
$200k-$220k/yr RemoteFull Time
SmarterDx
SmarterDx: AI-powered clinical documentation and revenue integrity for hospitals.
Lead ML research and development, deploy models, collaborate with engineers and clinicians; strong deep learning, MLOps, and publication track record.
PyTorch, Python, JAX, GitHub, Snowflake, Huggingface Transformers, AWS Sagemaker, Microsoft DeepSpeed, TorchTune, Apache Airflow, SLURM, Kubernetes
3w
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Research Scientist
United Kingdom or United States
RemoteFull Time
Prolific
Prolific: Platform connecting researchers with verified participants for human data collection.
PhD in a quantitative field; strong online research methods; lead research projects; proficiency in R, Python, or Qualtrics; self-driven; high output; based in US East Coast or UK.
R, Python, Qualtrics
1w
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Senior Quantitative Finance Analyst
Chicago or Jersey City or Pennington
$125k-$210k/yr OnsiteFull Time
Bank of America
Bank of AmericaNYSE: BAC: Provides global banking, investment, and wealth management services.
5+ YOELead development of market risk models, analyze risk, and collaborate with stakeholders. Strong Python, 5+ years of experience in pricing or market risk models; degree in quantitative field.
Python
2w
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Senior Director Data Science
United States
$203k-$231k/yr RemoteFull Time
Circana
Circana: Providing market research and consumer behavior analytics solutions.
10+ YOE5+ Mgmt10+ years software development; 5+ years ETL Spark; 5+ years leading distributed teams; strong Spark, Python, Scala, SQL; cloud experience (Azure/AWS).
Databricks, Spark, PySpark, Scala, Python, SQL, UNIX shell scripting, Azure, AWS, Snowflake, Synapse, Google BigQuery, Ab Initio, Hadoop, HBase, Data Modeling, Database Design, SDLC methodologies
1mo
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Principal Engineering Manager
United States
$160k-$425k/yr RemoteFull Time
GitHub
GitHubNASDAQ: MSFT: AI-powered developer platform for software collaboration and code hosting.
11+ YOE5+ Mgmt11+ years in software engineering or related field; experience leading distributed systems and AI infrastructure; strong people leadership.
C, C++, C#, Java, JavaScript, Go, Ruby, Rust, Python
1mo
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Principal API Architect
United States
RemoteAll Commitments Available
TeleWorld Solutions
TeleWorld SolutionsKRX: 005930: Design, deployment, and optimization services for wireless network infrastructure.
10+ YOELead API architecture for 4G/5G exposure; design and govern NEF/SCEF/CAMARA APIs; drive API standards and security.
Java, Kotlin, Go, Python, TypeScript, Node.js, C++, OpenAPI, REST, GraphQL, gRPC, OAuth2, mTLS, JWT, Cloud, Kubernetes, Containers, Service Mesh
3w
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(Senior) Engineering Manager, Platform/Back End
United States
$200k-$240k/yr RemoteFull Time
SentiLink
SentiLink: Provides identity verification and fraud prevention for financial institutions.
3+ YOE3+ Mgmt3-5+ years of engineering management leading backend/platform teams; strong backend engineer; API-driven systems; distributed systems; production backend architecture; startup growth experience.
React, Golang, Python, PostgreSQL, Docker, OpenSearch, AWS
1mo
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Manager, Engineering | QA
Seattle or Remote or United States
$170k-$180k/yr RemoteFull Time
ExtraHop
ExtraHop: Provides network detection and response software for cybersecurity.
6+ YOE2+ Mgmt7+ years in software quality engineering; 2+ years leading QA teams; BS in CS or related field; strong SDLC/CI/CD, automation strategy, cross-functional influence.
Python, Selenium, BDD/Behave, CI/CD, Test automation frameworks, AWS, Azure
2mo
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Head of Decision Intelligence
United States
RemoteFull Time
Deepgram
Deepgram: Developing AI-powered speech recognition and text-to-speech APIs.
7+ YOE2+ Mgmt7+ years in data/analytics with 2+ years leading teams; expert SQL and Python; build agentic, autonomous data systems; founder mindset; experience with usage-based SaaS metrics; hands-on data infra development.
SQL, Python, dbt, Hex
1mo
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Engineering Manager, Billing
United States
$125k-$178k/yr RemoteFull Time
Consensus Cloud Solutions
Consensus Cloud SolutionsNASDAQ: CCSI: Provides secure cloud fax and healthcare data interoperability solutions.
12+ YOE5+ Mgmt12+ years software development; 5+ years leading cross-functional architecture; expert Java; polyglot Python/Node.js/VB6; SOX/PCI-DSS; distributed systems; data-driven problem solving; coaching; change management.
Java, Python, Node.js, VB6, SQL
2mo
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Research Associate II - NE
Chicago, Illinois, United States
$30-$49/hr OnsitePart Time
Shirley Ryan AbilityLab
Shirley Ryan AbilityLab: Provides physical rehabilitation care and translational medical research services.
3+ YOEExtensive biomedical research training; advanced statistics; ability to lead and communicate results; manage lab activities.
Matlab, Python, R, Statistical Analysis
1mo
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AI Sustainability Consultant (Remote, Remote, US)
United States
$100k-$120k/yr RemoteFull Time
Bureau Veritas
Bureau VeritasEuronext Paris: BVI: Provides global laboratory testing, inspection, and certification services.
7+ YOEExperience leading sustainability consulting engagements, client relations, project management, and developing sustainability strategies.
Python, R, SQL, PowerBI
1mo
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Director, MDM Integrations (Chicago) (Chicago, IL, US)
Chicago, Illinois, United States
$160k-$175k/yr OnsiteFull Time
Fitch Group
Fitch Group: Provides global credit ratings and financial market research services.
5+ YOE5+ Mgmt5-7+ years leading data engineering teams; financial services and cloud (AWS/Azure); strong AWS expertise; AI/ML in engineering; strong Python and API development; REST/GraphQL; ETL/ELT pipelines; data governance/tools; product-led delivery and stakeholder communication.
AWS, Python, PostgreSQL, Redshift, Kafka, Kafka/MSK, S3, Glue, RDS/Aurora, Airflow, API Development, FastAPI, GitHub, Kubernetes, Redis
1w
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Senior Health Services Researcher- Remote
United States
RemoteFull Time
Community Health Center
Community Health Center: Provides integrated primary, dental, and behavioral healthcare services.
3+ YOELead health services research using EMR/EHR, claims data; strong biostatistics/epidemiology; experience with primary care, FQHCs; leadership and grant experience.
Python, SAS, Stata, R, Machine Learning, NLP
1mo
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Senior Director Data Science
Chicago, Illinois, United States
$162k-$300k/yr OnsiteFull Time
Health Care Service Corporation
Health Care Service Corporation: Provides health insurance and managed care to millions of members.
11+ YOE4+ MgmtLead data science initiatives; manage analysts; develop predictive models; drive data-driven decisions.
Python, SQL, R, Machine Learning, Data Visualization, Excel, PowerPoint, Hadoop, Spark
6d
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Market & Business Intelligence Manager
Reston or Atlanta or Austin or Baltimore or Boston or Chicago or Dallas or Houston or Los Angeles or Miami or Minneapolis or Philadelphia or Phoenix or Raleigh or San Diego or Seattle or Short Hills or Washington DC or Wilmington
$113k-$165k/yr HybridFull Time
DLA Piper
DLA Piper: Global law firm providing comprehensive legal and business services.
8+ YOELead analytics team; develop analytics strategy; collaborate with senior leaders; strong leadership and data analytics skills.
Azure, Fabric, Python, R, SQL, Power BI, Tableau
1w
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Principal Research Scientist – Value Based Payment Expert
Washington or Chicago
$171k-$220k/yr HybridFull Time
NORC at the University of Chicago
NORC at the University of Chicago: Conducts objective social science research and public policy analysis.
12+ YOE5+ MgmtSenior health policy researcher with 12+ years in value-based payment models; 5+ years leading projects; expertise in Medicare/Medicaid policy and CMS programs; strong communication and leadership skills.
Python, SQL, Stata, SAS, R
1mo
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Principal Research Scientist – Vision AI, Simulation & Physical AI
United States
$350k-$400k/yr RemoteFull Time
Centific
Centific: Providing data curation and platforms for scalable AI deployment.
5+ YOEPhD in Computer Science, Robotics, ML, CV, autonomous systems; 5+ years research; strong publications; lead large-scale AI research; proficiency in PyTorch/JAX and AI hardware; mentorship experience.
PyTorch, JAX, Hugging Face, xFormers, Isaac Sim, MuJoCo, OpenUSD/Omniverse, Open3D, Python, Ray, FastAPI, Docker, Kubernetes, Triton, TensorRT, Weights & Biases
2w
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Engineering Manager
United States or Canada or New Zealand
$150k-$190k/yr RemoteFull Time
Elation Health
Elation Health: Provides a clinical-first cloud EHR for independent primary care.
5+ YOE2+ Mgmt5+ years software development; 2+ years leading a team; API experience; strong communication; interest in AI/LLMs.
Python, MySQL, React, AWS, OpenAI, Anthropic
1mo
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Data Engineering Associate Director (Microsoft Fabric & Databricks)
Chicago, Illinois, United States
$162k-$276k/yr HybridFull Time
Protiviti
ProtivitiNYSE: RHI: Global consulting firm providing risk management and internal audit services.
9+ YOELead data engineering initiatives using Microsoft Fabric and Databricks; manage client engagements; mentor teams; develop data strategies.
Microsoft Fabric, Azure Databricks, Power BI, SQL, Python, Spark, Git, Microsoft Purview, Azure Storage, Azure DevOps
1mo
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Director of Analytics
Oak Brook, Illinois, United States
$154k-$196k/yr OnsiteFull Time
UNITE HERE HEALTH
UNITE HERE HEALTH: Administers healthcare benefits for hospitality and gaming union workers.
8+ YOE3+ MgmtLead enterprise analytics for healthcare cost trend; develop predictive models; guide data strategy and governance; build high-performing team.
SQL, Python, R, Power BI, Tableau
1w
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Allowance for Loan Losses Manager
United States
$119k-$188k/yr RemoteFull Time
Flagstar
FlagstarNYSE: FLG: Provides personal banking, mortgage lending, and commercial financial services.
10+ YOELead ACL production, analyze drivers of losses, develop qualitative adjustments, ensure GAAP/regulatory compliance, document processes, manage staff.
Python, SQL, Alteryx
1mo
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Senior Associate, Commercial Finance and Economics
Chicago, Illinois, United States
$125k-$140k/yr OnsiteFull Time
Invenergy
Invenergy: Develops, builds, and operates large-scale sustainable energy infrastructure projects.
4+ YOELead financial modeling and analysis for utility-scale energy projects; develop business cases; assess market and regulatory risks; collaborate with cross-functional teams.
Excel, VBA, Pivot tables, Lookups, Macros, PowerPoint, MATLAB, Python
2mo
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Sr. Engineering Manager Digital AI
Chicago or Waukesha
$152k-$228k/yr HybridFull Time
GE HealthCare
GE HealthCareNasdaq: GEHC: Manufacturing medical imaging systems and digital health solutions.
4+ YOELead cross-functional AI/software teams; drive digital AI product development; 4+ years in complex tech products (8+ with BS) and proven leadership.
Python, Machine Learning, AI, Software Engineering, Cloud
2mo
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Engineering Manager - Application Development
United States
$150k-$180k/yr RemoteFull Time
Bluesight
Bluesight: Software platform for hospital pharmacy and medication intelligence.
Lead two cross-functional teams; remote US; strong technical background; experience with Java Spring Boot, Python FastAPI, React, and healthcare tech; guide architectural decisions.
Java Spring Boot, Python FastAPI, React, MongoDB, Relational datastore, AWS
1mo
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Director of Engineering
United States
$195k-$215k/yr RemoteFull Time
Fluxx
Fluxx: Cloud software for managing the end-to-end grantmaking lifecycle.
8+ YOE3+ Mgmt8+ years in software with 5+ years as IC; 3+ years leading distributed teams; strong Ruby on Rails; SaaS enterprise experience; AI-first development experience; cloud, data, and architecture focus.
AWS, Elasticsearch, Unix, Redis, Node.js, Python, SQL, Play Framework

HiringCafe market data

Lead Python Developer Jobs market signals in Illinois, United States

These signals come from live HiringCafe job inventory, not a static article. Use them to compare the market, then open listings above to apply directly.

Open jobs
430+
Hiring companies
260+
Fresh sample
37% new in 30d
Salary visibility
71% show pay

Companies appearing in this market

ProlificAncestryBank of AmericaBlue OriginBluesightBureau VeritasCentificCircana

Work location mix in visible results

Remote: 30Onsite: 7Hybrid: 4