Lead Python Developer Jobs in Illinois, United States

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Peach Pilot — Principal QA Engineer

United States

RemoteFull Time

Hive Financial Systems: Provides AI-powered software and management systems for lenders.

7+ YOE7+ years QA engineering; 3+ years in lead/senior role; hands-on test code; AI/LLM testing; build and lead QA team; Python; CI/CD; multi-service integration; enterprise data/testing.

Python, React, TypeScript, Node.js, Neo4j, Snowflake, Azure Cosmos DB, Azure AI Search, Azure Functions, CI/CD

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Staff Site Reliability Engineer

Chicago, Illinois, United States

$132k-$220k/yr HybridFull Time

CME GroupNASDAQ: CME: Operates global derivatives marketplaces for trading futures and options.

10+ YOE3+ Mgmt10+ years in SRE/Systems/Software engineering; 3+ years in a staff/principal/tech lead role; experience leading cloud migrations or re-architecting platforms; GCP/Kubernetes; Python; Go; financial/regulatory environment familiarity.

Python, Go, Kafka, Kubernetes, GCP, Terraform, ArgoCD, Node.js

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Staff Engineer - Ads Trust, Fraud and Safety

United States

$217k-$304k/yr RemoteFull Time

RedditNYSE: RDDT: Social platform for community-driven discussion and content sharing.

7+ YOE7+ years software engineering; backend experience; leadership and communication skills; proficient in Go, Python, Scala, Java, or C++; able to lead large-scale projects.

Go, Python, Scala, Java, C++

2mo

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2mo

Principal Data/AI Engineer

United States

RemoteFull Time

FujifilmTokyo Stock Exchange: 4901: Manufactures imaging, medical diagnostic, and document innovation technologies.

12+ YOELead data/AI platform design, develop scalable pipelines, and mentor engineers; ensure data quality, observability, and regulatory compliance.

Python, SQL, dbt, Airflow, Snowflake, Snowpipe, Snowpark, Iceberg, Kubernetes, Docker, AWS, Azure

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AI Research & Development Lead

North America

RemoteFull Time

Intelehealth: Developing open-source telemedicine platforms for underserved populations.

10+ YOEAdvanced degree in ML/biomedical engineering/computer science; 6+ years total experience; leadership of AI/ML teams; healthcare AI deployment experience.

Python, Machine Learning, LLM, System Design, RAG, Multimodal systems, SaMD design

2mo

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2mo

Senior AI/Data Engineer

United States

$160k-$180k/yr RemoteFull Time

WorkWave: Cloud software for field service and fleet management operations.

5+ YOE5+ years data engineering; 1–2+ years in senior/lead capacity; Python, SQL; ML/AI enablement; data pipelines; cloud platforms; strong communication.

Python, SQL, Scikit-Learn, Airflow, dbt, Dagster, Snowflake, BigQuery, Redshift, Databricks, AWS, GCP, Azure

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Principal Data Platform Engineer (US)

United States

RemoteFull Time

Donnelley Financial SolutionsNYSE: DFIN: Provides financial regulatory compliance and reporting software solutions.

8+ YOELead data platform design and implementation; strong Python/PySpark, SQL; Azure Fabric/OneLake; 8–10 yrs data engineering experience.

Python, PySpark, SQL, Microsoft Fabric, OneLake, Azure Data Factory, Delta Lake, Parquet

2mo

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2mo

Staff Full-Stack Engineer (Team Lead) (Copy)

United States

$200k-$250k/yr RemoteFull Time

Helm Health: Building infrastructure for dynamic copay health insurance plans.

10+ YOE10+ years software engineering; hands-on technical leader; backend services, cloud, data systems, frontend architecture; experience managing engineering managers; Go and TypeScript; PostgreSQL, BigQuery, Redis, Firestore; GCP experience; Docker/Kubernetes.

Go, TypeScript, PostgreSQL, BigQuery, Redis, Firestore, Google Cloud Platform, Docker, Kubernetes, Python, Terraform, incident.io, Sentry, Drata, Cloudsmith, HCP Terraform, macOS, Linux

1mo

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1mo

Lead Associate Principal, Quantitative Risk Management

Chicago, Illinois, United States

$129k-$230k/yr OnsiteFull Time

Options Clearing Corporation: Provides clearing and settlement services for equity derivatives markets.

7+ YOEFinancial math, econometrics, programming (Python/Java/C++/R), data analysis, model development, QA, and documentation for risk models.

SQL, Python, R, MATLAB, Java, Git, Confluence, LaTeX, Excel

2mo

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2mo

Staff Product Test Engineer - Rolling Meadows, IL

Rolling Meadows, Illinois, United States

$110k-$130k/yr OnsiteFull Time

Epiq Solutions: Develops software-defined radio products and wireless sensing solutions.

8+ YOEEight+ years in NPI, automated test equipment software, Python preferred; lead NPI projects; strong OO programming and RF knowledge.

Python, Linux, GPIB, Serial, Ethernet, Qt

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Principal Engineer, LLM (Platform and Tooling)

United States

$238k-$330k/yr RemoteFull Time

UpstartNasdaq: UPST: AI-powered lending marketplace for consumer and automotive loans.

8+ YOEBachelor’s degree in Computer Science, Engineering, or Mathematics (or equivalent) with 8+ years of experience; strong LLM infrastructure and platform experience; proficient in Python, ML/LLM tooling, and scalable architectures; ability to lead cross-functional initiatives and define multi-year roadmaps.

LangChain, LlamaIndex, OpenAI APIs, Kubernetes, Docker, Terraform, Python, FastAPI, Kotlin, Spring, React, TypeScript

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JIRA Engineer

United States

RemoteFull Time

Dynamic Solutions Technology: Provides IT, engineering, and program management services to government agencies.

Lead Jira migrations, configure Gov Cloud, and ensure data integrity; strong Jira architecture and API skills required.

Jira, Jira Gov Cloud, Atlassian Cloud, Migration tools, Groovy, Python, API, CSV imports

2mo

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2mo

Data and Software Solutions Technical Lead

United States

$40-$55/hr RemotePart Time

Craig Technologies: Provides engineering, manufacturing, and technical services for aerospace and defense.

8+ YOE6+ Mgmt8+ years full-stack experience; 6+ years leading/mentoring engineers; part-time; remote; US citizen; NASA background check and ability to obtain security clearance.

React, Next.js, Python, Go, Node.js, GraphQL, REST, Docker, Kubernetes, Terraform, CloudFormation, AWS, Azure, PostgreSQL, MongoDB, DynamoDB

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Data & Insights Lead (US)

United States

RemoteFull Time

Volkswagen GroupFrankfurt Stock Exchange: VOW3: Global manufacturer of motor vehicles and automotive financial service provider.

7+ YOE7+ years in data visualization and product development; Bachelor’s in Business Analytics, Data Science, or related field.

Tableau, SQL, Python

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Infrastructure Engineer

United States

RemoteFull Time

Harrington Process Solutions: Distributes and fabricates industrial fluid process and flow control products.

3+ YOE3+ years infrastructure engineering; experience with Windows, Unix/Linux, networking, and cloud platforms; experience leading or contributing to technical projects; knowledge of cloud environments and scripting a plus.

Windows, Linux/Unix, Networking, Cloud (AWS/Azure/GCP), Containers, IaC, Configuration management, Python, PowerShell

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Security Engineer

United States

RemoteFull Time

Move Industries: Develops a Layer 1 blockchain network using the Move language.

Experience auditing security of blockchain protocols and smart contracts; strong code-level security skills; proficient in Move, Solidity, and Rust; able to build security tooling and lead incident response.

Move, Solidity, Rust, Python

1mo

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1mo

Lead or Senior Computational Chemist

United States

$100k-$400k/yr RemoteFull Time

Meliora Therapeutics: Develops machine learning platforms for cancer drug discovery.

5+ YOE2+ MgmtPhD in Chemistry or related; lead or senior experience in drug discovery; expertise in cheminformatics, molecular modeling, and ML; proficient in Python, RDKit, ML libraries; cloud experience; remote-friendly.

RDKit, OEchem, TensorFlow, Keras, PyTorch, Pandas, Scikit-Learn, DeepChem, GCP, AWS, Azure, Python, Git

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Staff Threat Detection Engineer

United States

$175k-$240k/yr RemoteFull Time

Chainalysis: Blockchain data platform for cryptocurrency investigation and compliance.

8+ YOE8+ years in detection engineering, SOC, or incident response; strong SIEM/EDR/log analytics expertise; proficient in detection queries (KQL, SPL, SQL); experience across endpoints, identity, and cloud; strong Python/Bash scripting; able to lead cross-functional security initiatives.

SIEM, EDR, Log Analytics, AWS, GCP, Python, Bash, KQL, SPL, SQL, MITRE ATTACK

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Sr Electrical Engineer

United States

$125k-$172k/yr RemoteFull Time

Sierra Space: Develops spacecraft and infrastructure for orbital and space transportation

8+ YOEBachelor's degree or equivalent; 8+ years experience; expertise in power/control/EWIS/CD&H; strong mentoring; lead complex electrical designs.

Capital, AutoCAD Electrical, Altium Designer, SPICE, MATLAB/Simulink, Hyperlynx, PCB Design, C/C++, Python

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Sr. Quality Engineer

United States

$95k-$110k/yr RemoteFull Time

RealTime eClinical Solutions: Provides cloud-based clinical trial management software solutions.

Senior QA engineer for manual and automated testing across web, mobile, and API apps; lead testing, build automation frameworks, ensure regulatory compliance.

Playwright, Postman, ReadyAPI, Python, JavaScript, Jenkins, GitHub Actions, Git, Xray, Lamda Test, Browserstack

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Platform Engineer

United States

$139k-$183k/yr RemoteFull Time

Cityblock Health: Provides integrated medical, behavioral, and social healthcare services.

6+ YOESix+ years in platform/infrastructure/DevOps; two+ years leading initiatives; strong Terraform and GCP experience; security/compliance focus (HIPAA, SOC 2); experience with CI/CD; familiarity with AI coding tools; able to work across teams.

Terraform, GCP, Cloud Run, BigQuery, GCS, Cloud Functions, Datadog, Github Actions, Tonic, Apollo, dbt, Python, CI/CD

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Principal Cloud Engineer

United States

$133k-$190k/yr RemoteFull Time

Enlyte: Provides technology and clinical services for insurance claims management.

12+ YOESenior AWS expert with 12+ years, design and lead scalable AWS infrastructure, security, and platform architecture.

AWS, Terraform, Kubernetes, CloudFormation, Python, Ansible

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AI Engineer III

United States

$94k-$165k/yr RemoteFull Time

CareSource: Provides public health insurance plans and care management services.

5+ YOELead AI engineer responsible for LLMOps, Azure AI Foundry, and CI/CD for ML models; 5 years IT engineering with 3+ years in DevOps/MLOps/Cloud infra; Azure/Kubernetes experience.

Python, Terraform, Bicep, ARM templates, MLflow, Prompt Flow, Azure AI Services, AKS, Kubernetes, API Management, Azure Monitor, App Insights, Vector Databases, RAG

2mo

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2mo

Staff Security Engineer

United States

$239k-$275k/yr RemoteFull Time

Garner Health: Identifies high-quality healthcare providers using medical claims data.

Lead technical security design, automate defenses, mentor engineers, own security domains; strong judgment and stakeholder management.

Python, Kubernetes, Snowflake, AWS, Terraform, Wiz, Cyberhaven

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Electrical Engineer | HPC Infrastructure

Chicago or New York City

OnsiteFull Time

Jump Trading: Global proprietary trading firm specializing in algorithmic and high-frequency strategies

7+ YOELead electrical design for mission-critical HPC data center infrastructure; PE license required; 7+ years experience; strong communication and project leadership.

Revit, AutoCAD MEP, BIM, NEC, NFPA, IEEE, Python, AI tools

1mo

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1mo

Principal Platform Engineer

United States

$174k-$187k/yr RemoteFull Time

Coforma: Designs and builds digital solutions for the public good.

8+ YOE8+ years in Platform/SRE/DevOps; senior/tech lead; strong GCP, observability, IaC; containerized services; SRE/DevSecOps; US residency.

GCP, GitHub, Datadog, Grafana, OTEL, Prometheus, Sentry, Incident.io, Terraform, Pulumi, Docker, Kubernetes, Python, JavaScript, Bash, Go, Rust

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Senior Sales Engineer, Enterprise

United States

$158k-$198k/yr RemoteFull Time

Fivetran: Automates data movement into cloud data warehouses.

5+ YOE5+ years in enterprise IT sales or sales engineering; strong knowledge of RDBMS and cloud data warehouses; ability to lead POC and coordinate cross-functional teams; excellent communication.

AWS, GCP, Azure, Snowflake, BigQuery, Databricks, Kafka, Grafana, APIs, Linux, Windows, Python, Java, Relational Databases

2mo

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2mo

Industry 4.0 Engineer (Ignition)

Chicago or Detroit

$75k-$125k/yr HybridFull Time

ReplyBorsa Italiana: REY: Provides IT consulting, digital services, and systems integration services.

Lead design, implement, and optimize Industry 4.0 solutions with IoT, automation, AI, and data analytics.

Ignition, C#/.NET, SQL, Python, JavaScript, MQTT

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Digital Technology Lead – Vin & Catalog Modernization

Lisle, Illinois, United States

$138k-$206k/yr OnsiteFull Time

International MotorsXETRA: 8TRA: Manufacturer of commercial trucks, buses, and heavy-duty engines.

3+ YOEBachelor's or Master's in a related field with 3+ years (Masters) or 5+ years (Bachelor) of software engineering; leadership experience.

Node.js, TypeScript, Python, Cloud-native Databases, Elasticsearch, Algolia, AI coding assistants

2mo

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2mo

Senior Data Engineer

Chicago or Birmingham or Dallas or Jacksonville or Richardson

$99k-$165k/yr HybridFull Time

KemperNYSE: KMPR: Provides specialized auto and life insurance to underserved markets.

8+ YOE8+ years data engineering; senior/lead/architect experience; Snowflake, AWS, data vault 2.0, ELT/ETL, SQL proficiency; strong leadership and collaboration.

Snowflake, Python, Spark, Informatica, AWS Glue, Control-M, Airflow, Snowflake Scripting, SQL, ETL/ELT, GitHub Actions, GitLab CI, Azure DevOps, Terraform, CloudFormation, Great Expectations, Monte Carlo, Datafold, Soda, Alation, Collibra

2mo

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2mo

Senior Solutions Engineer

United States

$160k-$200k/yr RemoteFull Time

Junction: Infrastructure for connecting healthcare diagnostic labs and wearables.

Senior Solutions Engineer for API-first B2B products; leads pre-sales conversations, onboarding, and integration; handles security/compliance questions (HIPAA, SOC 2, BAAs); remote-friendly.

Python, Go, PostgreSQL, Google Cloud Platform, Temporal, TypeScript, Next.js

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Principal Project Engineer, ES

United States

$150k-$170k/yr RemoteFull Time

Anza: Software marketplace for solar and energy storage equipment procurement.

5+ YOELead technical design and execution of energy storage projects; review deliverables; coordinate commissioning; mentor engineers; ensure standards compliance.

AutoCAD, ETAP, PSSE, PSCAD, PSLF, Python, Excel, Wireshark, Modbus, DNP3, CAN

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Dir Applied AI Engineer

United States

$168k-$268k/yr RemoteFull Time

One Call: Coordinates healthcare services for workers' compensation insurance claims.

7+ YOELead engineering team building production AI systems; 7+ years leadership; shipped AI to production; experience with LLMs; regulated industry experience.

Python, LLM, Data Pipelines, Cloud Platforms, Docker, Kubernetes

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Software Engineer Manager

United States

RemoteFull Time

IMG Academy: Provides sports-focused boarding school education and athletic training camps.

5+ YOE2+ Mgmt5+ years backend or full-stack software engineering; 2+ years in engineering management or tech lead; experience with distributed systems, cloud (AWS), 12-factor apps, CI/CD, databases; strong communication; on-call readiness.

Python, Go, Kubernetes, AWS, PostgreSQL, Redis, OpenSearch, Kafka, Auth0, Shopify, Contentful

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Senior Data Engineer

United States

RemoteFull Time

Mission Underwriters: Platform providing infrastructure for independent insurance underwriting programs.

5+ YOE5+ years in data engineering/data warehousing; 3+ years in commercial insurance; Azure data services; strong SQL; dimensional modeling; data ingestion; BI tools; Git; Bachelor's degree in CS/Engineering/IS; ability to lead implementations.

Azure, SQL, Power BI, Looker, Tableau, GitLab, dbt, Python

1mo

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1mo

Sr. Network (DevOps) Engineer

Scottsdale or San Francisco or Chicago or New York

$106k-$156k/yr HybridFull Time

Early Warning Services: Operates payment and risk solutions for the financial industry.

5+ YOEDesign, implement, and support complex network solutions across LAN/WAN/Data Center/Cloud; lead initiatives; strong hands-on with Cisco/Palo Alto, AWS, scripting.

Cisco, Palo Alto, F5, AWS, Terraform, AWS CloudFormation, Ansible, Python, Bash

2mo

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2mo

Client Engineer III (MedInsight)

Seattle or Appleton or Atlanta or Boise or Wakefield or Chicago or Dallas or Hartford or Omaha or San Francisco or Portland or Portland

$85k-$162k/yr RemoteFull Time

Milliman: Provides actuarial consulting and risk management solutions globally.

5+ YOE5+ years in analytics/data engineering with client-facing delivery; expert SQL; dimensional modeling; strong software engineering practices; able to lead data-driven implementations.

SQL, Git, CI/CD, ETL, Data Modeling, Python, Cloud

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Knowledge Engineer / Semantic Expert for AI

Mountain View or Milwaukee or Dallas or Columbus or Kirkland or Cincinnati or New York or Cleveland or Oklahoma City or Austin or Albany or Chicago or St. Petersburg or Hartford or Pittsburgh or St. Louis or Miami or Sacramento or Raleigh or Minneapolis or Scottsdale or San Francisco or Morristown or Denver or Boston or Philadelphia or Des Moines or Overland Park or Los Angeles or Charlotte or Walnut Creek or Carmel or Seattle or Houston or Arlington or Atlanta or Redmond or Bentonville or Beaverton or Nashville or Detroit or San Diego

HybridFull Time

AccentureNYSE: ACN: Global provider of management consulting and technology services.

12+ YOELead Knowledge Graph and AI solutions; design ontologies; build end-to-end data pipelines; team leadership; strong RDF/graph DB expertise.

RDF, SPARQL, LPG, SHACL, Neo4J, Stardog, Amazon Neptune, Python, TensorFlow, PyTorch, Airflow, NiFi, LLMs

2mo

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2mo

Senior Security Operations Engineer

United States

RemoteFull Time

Sword Health: AI-driven clinical care for physical and mental health.

Design and improve detection and incident response; automate runbooks; lead investigations; cloud security, scripting, and SOC tooling expertise; ability to obtain and maintain US Public Trust clearance.

SIEM, SOAR, EDR/XDR, Python, Bash, AWS, GCP, Azure